Hardee Cross Roads, North Carolina is halfway between Columbia & Virginia Beach
If that's Myrtle Beach, it's in South Carolina. The halfway point is Enfield, North Carolina.
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Chesterfield VA is about halfway from Allentown to Myrtle Beach.
Tylersville, South Carolina is halfway between Columbus & Daytona Beach
The city between Asheville, NC and Myrtle Beach, SC is Columbia, South Carolina which is only about six miles from the exact midpoint. However, the town that marks the exact halfway point is actually Saint Andrews, South Carolina.
The distance between Clarlotte, NC and Miami Beach, FL is about 730 miles. The midpoint would be near Jacksonville, FL.
On US-17, New Bern, North Carolina is exactly the halfway point.
It's approximately 150 miles between Columbia, SC and Myrtle Beach, SC (and will take almost three hours.)
The halfway point is the North Carolina/ South Carolina border where that annoying South of the Border hotel is. When I make that trip, I drive one more exit south, to Florence, South Carolina.
Interstate 40, Sayre, OK 73662, USA
Oak Forest, Arkansas is halfway between Manhattan & Panama City Beach