A hemolytic disease of the newborn that is characterized by an increase in circulating red blood cells and by jaundice and that occurs when the system of an Rh-negative mother produces antibodies to an antigen in the blood of an Rh-positive fetus which cross the placenta and destroy fetal red blood cells, called also hemolytic disease of the newborn.
Hemolytic disease of the newborn is known as erythroblastosis fetalis
IgG is the class of immunoglobulin responsible for the development of erythroblastosis fetalis. It can cross the placenta from a mother who is Rh-negative to a fetus who is Rh-positive, leading to hemolytic disease in the newborn.
Hemolytic disease of the newborn is also known as erythroblastosis fetalis. It is a condition that develops in a fetus when the mother and fetus have incompatible blood types.
Parents who are expecting a baby have their blood typed to diagnose and prevent hemolytic disease of the newborn (HDN), a type of anemia also known as erythroblastosis fetalis.
Cyril Astley Clarke has written: 'Prevention of Rh-hemolytic disease' -- subject(s): Erythroblastosis fetalis, Prevention 'Human genetics and medicine' -- subject(s): Medical genetics
I'm not sure If I'm right. Hemolytic - Means Breaking down Red Blood Cells. Erythroblastosis - Refers to making of immature red blood cells. Fetalis - Refers to Fetus.
The main concern is the risk of maternal antibodies attacking the Rh-positive fetal blood cells, leading to hemolytic disease of the newborn (HDN) or erythroblastosis fetalis. This can result in severe anemia, jaundice, and other complications in the newborn. Treatment with Rho(D) immune globulin can prevent this by suppressing the maternal immune response.
RHO Gam is used to prevent hemolytic disease of the newborn in cases of Rh incompatibility between the mother and fetus. It works by preventing the mother's immune system from producing antibodies that could harm the baby in future pregnancies.
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A Coomb's test will indicate the formation of antibodies on the red blood cell. This test can be used to determine blood type, and diagnose certain hemolytic anemias. A Coombs' test may also indicate the prescense of maternal antibodies against the fetal blood type as occurs in erythroblastosis fetalis.
It is when the mother has antibodies in her blood to the baby's blood group and the antibodies cross the placenta and start breaking down the baby's red blood cells causing hemolytic anemia. The most common is when a previously sensitised Rhesus Negative mother has a Rhesus positive baby, but ABO incompatibbility is not unknown. See the weblinks for further ionfromation.
Hemolytic anemia indicates the early destruction of red blood cells. This can occur as inherited or acquired hemolytic anemia. Certain medicines can cause acquired hemolytic anemia, please check with the doctor.