0
What else can I help you with?
Inadequate intrinsic factor is associated with?
Inadequate intrinsic factor is associated with vitamin B12 deficiency, as intrinsic factor is necessary for the absorption of this essential nutrient in the gut. Vitamin B12 deficiency can lead to symptoms such as anemia, fatigue, and neurological problems. It is commonly seen in individuals with pernicious anemia or autoimmune conditions affecting the stomach lining.
Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?
Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.
A protein secreted by the stomach that is necessary for the absorption of vitamin B12?
The protein secreted by the stomach that is necessary for the absorption of vitamin B12 is called intrinsic factor. Intrinsic factor binds to vitamin B12 in the small intestine, allowing for its absorption into the bloodstream. Without intrinsic factor, vitamin B12 cannot be effectively absorbed and can lead to a deficiency.
What sphincter is associated with the pancreas?
Sphincter of Oddi.
How does the muscle of the internal anal sphincter differ from that of the external anal sphincter?
The internal urethral sphincter an involuntary sphincter that keeps the urethra closed when urine is not being used. The external urethral sphincter is fashioned by skeletal muscles as the urethra passes thorugh the pelvic floor.This sphincter is voluntary controlled.
What is Type III of stress incontinence?
Type III: Hypermobility of the urethra where the primary source of incontinence is the inability of the sphincter muscles to keep the bladder closed. This is due to weakness or deficiency in the intrinsic sphincter muscles
What condition is treated with retropubic suspension?
to correct incontinence.Incontinence is common when either the urethra lacks tautness and stability (genuine stress urine incontinence, SUI) and/or the sphincter muscles are unable to keep the bladder closed (intrinsic sphincter deficiency, ISD).
What are some causes of sphincter deficiency?
Sphincter deficiency can result directly from pelvic fracture; urethral reconstruction; prostate surgeries; spinal cord injury; neurogenic bladder conditions that include sphincter dysfunction; and some congential conditions.
Why do you need intrinsic factor?
Intrinsic factor or gastric intrinsic factor is a protein produced by the stomach. It is used to absorb vitamin B12 in the small intestine. When there is a deficiency of the Intrinsic factor, there is a deficiency in the absorption of B12 into the body and this leads to pernicious anemia.
Inadequate intrinsic factor is associated with?
Inadequate intrinsic factor is associated with vitamin B12 deficiency, as intrinsic factor is necessary for the absorption of this essential nutrient in the gut. Vitamin B12 deficiency can lead to symptoms such as anemia, fatigue, and neurological problems. It is commonly seen in individuals with pernicious anemia or autoimmune conditions affecting the stomach lining.
What results from the hereditary lack of intrinsic factor?
Pernicious anemia (vitamin B 12 deficiency)
How pernicious anemia cause achlorhydria?
pernicious anemia is a vitamin B12 deficiency. Vitamin B12 requires Intrinsic Factor to be reabsorbed by the ileum. Intrinsic Factor is produced by parietal cells in stomach. If there is some damage or manipulation of parietal cells, which also produce HCl, there will be less of both intrinsic factor causing B12 deficiency and HCl causing achlorhydria.
Which nutrient requires intrinsic factor for absorption?
Vitamin B12 requires intrinsic factor for absorption in the small intestine. Intrinsic factor is produced by the stomach and binds to vitamin B12 to facilitate its absorption in the ileum. Without intrinsic factor, vitamin B12 absorption is impaired, leading to deficiency.
Which clinical condition would occur if intrinsic factor was not produced by t he gastric glands?
A b-12 deficiency.
What is the anatomical sphincter and what is the physiological sphincter?
Sphincters can be classified into functional and anatomical sphincters:Anatomical sphincters have a localised and often circular muscle thickening to facilitate their action as a sphincter.Functional sphincters do not have this localised muscle thickening and achieve their sphincteric action through muscle contraction around (extrinsic) or within (intrinsic) the structure.Sphincters can also be voluntarily or involuntarily controlled:Voluntary sphincters are supplied bysomatic nerves.Involuntary sphincters are stimulated byautonomic nerves.
Why oral administration of vitamin B12 not effective as a treatment of pernicious anemia?
Pernicious anemia is due to a deficiency of a vitamin called intrinsic factor, which is normally produced by cells of the stomach. Intrinsic factor is required for the absorption of vitamin B12, so if intrinsic factor levels are insufficient, vitamin B12 will not be absorbed well. So administration of vitamin B12 will only help treat vitamin B12-deficiency anemia if vitamin B12 can be absorbed, and this can only happen if there are adequate levels of intrinsic factor to begin with. Patients with pernicious anemia do not have adequate intrinsic factor levels, so they will not be helped by vitamin B12 treatment since they can't absorb it well enough.
The voluntary sphincter is the -----sphincter?
outer anal sphincter
