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Why do you need intrinsic factor?

Intrinsic factor or gastric intrinsic factor is a protein produced by the stomach. It is used to absorb vitamin B12 in the small intestine. When there is a deficiency of the Intrinsic factor, there is a deficiency in the absorption of B12 into the body and this leads to pernicious anemia.


When is vitamin B 12 poorly absorbed in the absence of?

Intrinsic Factor. This, also known as gastric intrinsic factor (GIF),isa glycoprotein produced by thestomach necessary for the absorption ofB12 there and in the small intestine.


Where producing gastric juice?

Gastric juice is produced in the stomach. Gastric juice is produced in the Gastric glands.


Is gastric acid the secretions in the gastric juice produced by the stomach?

Gastric acid is part of the "juices" produced by the stomach.


What is the function of the gastric canal?

the gastric canal has an important clinical role in the stomach as it allows for gastic juices to be removed before absorption


What organ is gatric juice produced?

Gastric juice is produced in the stomach. It is a digestive fluid composed primarily of hydrochloric acid, pepsinogen, and intrinsic factor, which aid in breaking down food and absorbing nutrients. The acidic environment also helps kill pathogens that may be ingested with food.


How many gastric juice are there?

Gastric juice is not classified into different types but is a complex mixture primarily composed of hydrochloric acid, pepsinogen, intrinsic factor, and mucus. These components work together to digest food and protect the stomach lining. The amount of gastric juice produced can vary based on factors such as diet and individual physiology, typically ranging from about 1.5 to 3 liters per day in a healthy adult.


Where is ghrelin produced?

Ghrelin is produced in the stomach and small intestine.


What is the literal meaning of gastric in biology?

The term "gastric" in biology refers to anything related to the stomach. For example, gastric acid is the acid produced in the stomach to help digest food.


What clinical trials are being conducted on MALT lymphoma?

Clinical trials are underway and mostly concentrate upon optimizing treatment of gastric MALT lymphomas that involve H. pylori.


Is hydrochloric acid necessary to produce the intrinsic factor for cobalamin?

No, hydrochloric acid (HCl) is not necessary to produce the intrinsic factor for cobalamin. HCl is needed along with gastric enzymes to free Cobalamin (B12) from its polypeptide linkages in food. The intrinsic factor involved with the digestion and absorption of Cobalamin (B12) is a glycoprotein.


What is pernicious anemia is cause by?

PA is caused by a deficiency of Intrinsic Factor (IF). IF is a required factor in Vitamin B12 absorption through the gastrointestinal tract. IF deficiency is diagnosed by Schilling's test, as well as Gastric IF analysis and clinical rpesentation (macrocytic megaloblastic anemia, often showing hypersegmented neutrophils, along with normal Folic acid levels).