Laminin is a Glycoprotein (Oligosaccharide-Protein) which acts as a binding agent between cell walls. They have been dubbed as the "babysitters" of the cells. Laminin influence the cells' differentiation, movement, adhesion, and cell life. Certain muscular dystrophy have been linked to malfunctions in the laminin (Laminin 211 for all you students of chemistry).
This is what Laminin looks like:
.........................O.......................
.........................O.......................
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............OO===|.|.|===OO.........
........................\|/.......................
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................................................
................................................
.........................O.......................
As you can see laminin look much like crosses. The three sections which combine are composed of a Beta chain, Alpha chain, and Gamma chain (respectively). Each chain has a double OO shaped Collogen IV base which acts as a "hand" grabbing onto a cellular wall. The three chains coil around each other and end at the bottom Herapan Sulfate Binding Domain (the bottom O).
http://www.med.unibs.it/~marchesi/extracellularmatrix.html
It looks like a cross of sorts..
Laminin protein work together with other proteins, laminin glyoprotein assist in creating structural building blocks for membranes in every human tissue and some animals. They are the glue (connective tissue) inside of us that holds, uniting force, a tie, one cell, to another cell creating a bond. They are the cheer leaders to promote cell adhesion. If we did not have them in our body we would fall apart.
dermal papillae, are small, nipple-like protrusions of the dermis that reach into the epidermis, bringing food and oxygen to the lower layers of epidermal cells. In addition, a papilla nourishes every hair follicle. Rows of papillae protruding from the dermis into the epidermis form ridges that create patterns on the skin of the hands, feet, and body. These papillary ridges on the fingertips are responsible for fingerprints. These ridges develop sometime before birth. Not only is the pattern unique for each individual, but also it never changes except to grow larger.
skin's most apical layer is full of keratin the tight jxn's holding the stratified squamous epithelium together use claudin and occludin there are a few more cellular jxn's that use other proteins as well there is type IV collagen laminin and proteoglycans in the basal lamina under the epitheluim then there is LOTS more collagen in the loose and dense connective tissue underneath. hope that helps!
Basal Lamina and glycoproteins are two of the functional groups that are present in laminin. Laminin is an active and biologically important part to both groups.
what dose laminin do for our bodies?It basically holds the cell-structures together, keeping them from falling apart.
laminin
the word - laminin - does not appear in the King James version of the Bible, nor in any English language version of the Bible
yes
http://www.med.unibs.it/~marchesi/extracellularmatrix.html
just shut up
It looks like a cross of sorts..
Truthfully no. The most that one can gather from a laminin is the diagram shape is of a cross. I have heard a few sermons and talks of how the laminin is a sign of God or a metaphor for the way Christ holds together the church, the world, or etc. I simply ask that we, as Christians, please leave these instances as merely metaphors. Do not use these in any apologetic conversations as they have no debatable merit.
yup. T shaped with blobs on the end. Have you googled integrin?
A cross-shaped cell is called a cruciform cell.
The genetic mutations for junctional EB are found in the genes responsible for producing the protein Laminin-5.