Appointment is to emergency
the Great Famine the Hundred Years' War the Black Plague
A plague caused Isaac to go home from college in Cambridge.
In 429 B.C, a plague came to athens and killed pericles and the leadership fell to inferior men.
I would have to say the Plague/Black Death and the Spanish Flu epidemic combined.
a huge catastrophe
No, catastrophe is a noun.
The earthquake in China was a major catastrophe.
U-Catastrophe was created in 2007.
Hijacking Catastrophe was created in 2004.
Causing a Catastrophe was created in 2002.
The Ultraviolet Catastrophe was created in 1998.
Catastrophe Ballet was created in 1984.