What is prekallikrein?

Anonymous

∙ 15y ago

Updated: 8/19/2019

Prekallikrein (PK), also known as Fletcher factor, is a 85,000 Mr serine protease that complexes withHigh-molecular-weight Kininogen. PK is the precursor of plasma kallikrein, which is a serine protease that activates kinins. PK is cleaved to produce kallikrein by activated Factor XII (Hageman factor).

Wiki User

∙ 15y ago

What else can I help you with?

What initiates coagulation?

When the blood vessel is injured, so is the endothelium, so it releases the endothelium tissue factor (TF), which complexes with factor VII, activating it, which then activates factor X and IX and the rest of the cascade continues.Collagen is also exposed to a molecular, called high molecular weight kininogen (HMWK), prekallikrein and Hageman factor (factor XII), forming a complex. Prekallikrein is converted to Kallikrein and factor XII is activated to produced factor XIIa, which then activates factor XI and then factor X (the common factor between those two pathways), and the rest of the cascade continues, till the formation of the blood clot.

Trending Questions

What is the latitude and longitude of Miami Florida? What is the social life in Sudan? What the jet aircraft used in World War 1? Am trying to call international to a mobile phone number to guatemala city and what is the number to be dialled before the 502 country code? What is a typical number on a line plot? 19 century German composer conductor Richard? How much salary for auto mechanics? How many records has nirvana sold? What is 22.5240 rounded to the nearest thousandths? Where does troy tulowitzki live? What is stone cycle? How many cL are in a dL? Who discovered Bahrain? Which of these passages from The Adventures of Huckleberry Finn contains a simile? Is it bad if your screen on woozworld is blue and not white? Does kian lawley wear glasses? What is the homonym of fine? How much does a sonar cost? Common factor of 40 and 48? Why is my fluorescent light flickering?

Resources

Top Categories

Product

Company

Copyright ©2026 Infospace Holdings LLC, A System1 Company. All Rights Reserved. The material on this site can not be reproduced, distributed, transmitted, cached or otherwise used, except with prior written permission of Answers.