What is prekallikrein?

Anonymous

∙ 15y ago

Updated: 8/19/2019

Prekallikrein (PK), also known as Fletcher factor, is a 85,000 Mr serine protease that complexes withHigh-molecular-weight Kininogen. PK is the precursor of plasma kallikrein, which is a serine protease that activates kinins. PK is cleaved to produce kallikrein by activated Factor XII (Hageman factor).

Wiki User

∙ 15y ago

What else can I help you with?

What initiates coagulation?

When the blood vessel is injured, so is the endothelium, so it releases the endothelium tissue factor (TF), which complexes with factor VII, activating it, which then activates factor X and IX and the rest of the cascade continues.Collagen is also exposed to a molecular, called high molecular weight kininogen (HMWK), prekallikrein and Hageman factor (factor XII), forming a complex. Prekallikrein is converted to Kallikrein and factor XII is activated to produced factor XIIa, which then activates factor XI and then factor X (the common factor between those two pathways), and the rest of the cascade continues, till the formation of the blood clot.

Trending Questions

What organelle is abundant in the muscle cells? Why does the use of a salt solution in Kimchi act as a preservative against bacterial decay? Which is greater either 15 percent of 380 or 25 percent of 210? How do you say l like jump rope in Spanish? Energy levels of an atom are occupied by what? What is U stands for in the serial number of marlin lever action rifle? What is meaning of moggie? is a insect a vertebrate or a invertebrate? Why cant Mary faint when asked by the court? When was Halicarnussus conqured by Alexander? What is pansexal? Did Hank Aaron ever play ball for the Minnesota Twins? Is friend an abstract noun or concrete noun? Can you get a payday loan with a negative balance in your account? How do you register an off road quad for the road? What is the percent of 4 out of 16? What are people who study the planets and start called? What is the journal entry to purchase asset from general reserve? How many confirmed extra solar planets have been up to date? What is a prefix for the word around?

Resources

Top Categories

Product

Company

Copyright ©2026 Infospace Holdings LLC, A System1 Company. All Rights Reserved. The material on this site can not be reproduced, distributed, transmitted, cached or otherwise used, except with prior written permission of Answers.