A proteoglycan is a protein + glycosaminoglycan a GAG
>20 porteoglycans genes
So then you have GAG which are the Glycosaminglycan attach to the core protein. This core protein.
The repeating core. This means they have glucuronic acid, or iduronic acid with the OOC attached to the sugar. With N-acetylgalactosamine-4-sulphate and they have the SO3 negative charge on them and this makes water/contains water.
They are attached to serine on the protein core.
Hyalurnan is not made in the same way. and is secreted in the wounds and other things.
Aggrecan aggregate has a hyaluronin molecule which is not created in the same way and attaches these proteins and they have keratin and chondronin sulphate.
Perican along with the basement membrane, act as a sieve for for the incoming molecules.
They mainly have 4 Functions which you need to basically remember
They hydrate space for the negative charges.
Selective sieves for regulation of molucules trafficing.
Major role in chemical signalling between the cells (growth factor signalling, FGF) So basic signaling.
And they bind proteisase.
Basal Lamina
Organic, for sure.
Actually, proteoglycans are conjugates of proteins and carbohydrates in which there is more carb and less protein. In fact, proteoglycans have GAGs (heteropolysaccharides) as carbohydrates. Glycoproteins, on the other hand, have more protein and less carb. Here, carbohydrates are in the form of Oligosaccharides.
Dentine and cementine contain specific proteins as proteoglycans, collagene and other.
That depends a bit on what your proteoglycans are and where in the body they are. I'm currently working the musculoskeletal field. I'm pretty sure I've seen it suggested that proteoglycans can act as lubricators and allow fibrils within organs such as tendons to slip past each other smoothly. I also know that the large proteoglycan aggrecan is a vital component of hyaline cartilage. It contains lots of negatively charged polysaccharide side chains which attract and retain water. This contributes to cartilage's ability to resist compressive forces.
Basal Lamina
Proteoglycans are organic compounds !
hydrated proteoglycans
YEs, it does..
Organic, for sure.
proteoglycans - heaprin sulfate , chondroitin sulfate , keratan sulfate , GAG's Non-proteoglycans - Hyaluronic acid collagen , elastin , fibronectin , laminin
glycoproteins
[protein molecules and] carbohydrate molecules.
due to sulfated proteoglycans
Cytoplasm and the extracelular matrix hold organells in place within the cells membrane. Cytoplasm contains mostly water, from 80 to 97% in different cells, and the Extracellular matrix is composed of glycoproteins and proteoglycans
Actually, proteoglycans are conjugates of proteins and carbohydrates in which there is more carb and less protein. In fact, proteoglycans have GAGs (heteropolysaccharides) as carbohydrates. Glycoproteins, on the other hand, have more protein and less carb. Here, carbohydrates are in the form of Oligosaccharides.
Anulus Fibrous