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Pyruvate is the result of glycolysis, the degradation of a molecule of glucose. In aerobic conditions (with O2 present), pyruvate is oxidized to H2O and CO2 via the citric acid cycle and oxidative phosphorylation to produce energy (ATP). In anaerobic conditions (low levels of O2), pyruvate metabolism goes in two directions: in yeasts, an alcoholic fermentation takes place (with the production of two CO2 molecules + two molecules of ethanol); while in muscle, homolactic fermentation occurs (with the result of 2 molecules of lactate).

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