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What is seroconversion rate?

Updated: 12/6/2022
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Q: What is seroconversion rate?
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What is Seroconversion?

Seroconversion is the point at which the immune system is stimulated into developing the antibodies needed to fight infection (or respond to immunization) by an antigen (an antigen is anything that stimulates an immune response - including viruses, bacteria, tumorous cells, things to which we become allergic etc). Seroconversion is frequently (but by no means always) associated with some form of seroconversion illness. In terms of an infection with HIV - the context in which the question was asked - it is important to note that it is the HIV antibodies devolved during the seroconversion process that are detected by the common HIV antibody test. It can take up to three months (the 'window period') for the immune response to be fully triggered and produce enough antibodies to be reliably detected by an HIV antibody test. HIV seroconversion illness generally takes the form of a mild fever / sore throat / rash / mild flu-like illness - some two to six weeks (up to three months) after HIV infection - but can occasionally be severe enough to require hospitalisation. The longer the illness lasts (and the more severe it is) the more likely the untreated patient is to develop AIDS within five years. Even before seroconversion takes place, an HIV infected person will generally have enough of the virus in their blood / sexual fluids / breast milk to infect another person - in fact they are frequently particularly infectious during the window period, before a full immune response has been triggered and the infection can be diagnosed.


Is a person with HIV contagious before seroconversion?

An infected person with HIV is contagious soon after initial infection. The highest risk of transmission is during the initial infection, and at the end stage near death.


What does very early hiv infection prior to seroconversion cannot be excluded mean?

Seroconversion refers to the development of antibodies after infection. There is a period of time between when a person is infected with HIV until they will test positive. This is often referred to as the "window period." Depending on the test, it could take up to 6 months for a person to test positive after being infected with HIV. This is because it takes a while for a person's body to develop the anitbodies associated with HIV infection that HIV tests use to detect infection.


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ANDREA MARIE ANONYCHUK has written: 'STRESSFUL RELATIONSHIP EVENTS AND HIGH-RISK SEXUAL BEHAVIOUR AMONG MEN WHO HAVE SEX WITH MEN ENROLLED IN THE POLARIS SEROCONVERSION STUDY'


Do some get AIDS on purpose?

Bugchasers seek sexual partners who are HIV positive for the purpose of having unprotected sex and seroconversion; giftgivers (also gift givers) are HIV positive individuals who comply with the bugchaser's efforts to become infected with HIV.See related link.


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