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Sickle-cell Anemia, or Sickle-cell Disease, is a disease which is caused by a mutation in the animo acid sequence of the red blood cells.

The type of mutation occurs during the transcription of messenger RNA (e.g. GTC becomes CCG instead of CAG ). This change causes the mRNA to translate into a different amino acid (e.g. Valine instead of Glutamate ).

In this disease, the changes start in amino acids, the primary structure of proteins, thus changing all the higher protein structures. The red blood cells then will have a different shape, like a sickle.

These sickle shaped red blood cells will nor function normally. Thier shape disables them from flowing easily in the blood vessels, which might lead to further complications. Also, their life span is shorter than the normal cells, hence causing Anemia.

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A chronic, inherited blood disorder characterized by crescent-shaped red blood cells. It occurs primarily in people of African descent, and produces symptoms including episodic pain in the joints, fever, leg ulcers, and jaundice.
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13y ago
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14y ago

There are several definitions of sickle:

In the Harry Potter series a sickle is a silver coin.

To farmers a sickle is a tool for cutting weeds or harvesting grain. It normally has a slightly curved blade and is on a short handle.

In Martial Arts, the sickle is known as a kama and is one of the traditional kabudo weapons.

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13y ago

Sickle Cell is a type of Anemia that means the red blood cells are deformed and sickle shaped. The hemoglobin in your body doesn't work right; the shape of the red blood cells causes them to clog the blood vessels and break down easily.

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14y ago

Sickle cell anemia is a disorder of the blood caused by an inherited abnormal hemoglobin. which is an oxygen carrying protein within the red blood cells. The abnormal hemoglobin causes distorted red blood cells. The sickled red blood cells are fragile and are prone to rupturing. When the number of red blood cells decrease from rupture, the result anemia.

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17y ago

Its a genetic type of anemia found in the black community. Check the Mayo Clinic medical information under Sicklecell anemia.

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15y ago

Sickle-cell in an ifection in your body. So if you get to hot or to cold your body reactes in a wierd way then you faint. The best thing to do is to keep right not to hot or not to cold.

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9y ago

Sickle cells are cells that are kind of a half moon shape, and they look kind of like the top of sickles. Having sickle cells can cause sickle cell disease.

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10y ago

The illness sickle cell anemia is a blood disease that occurs when the red blood cells have an irregular shape, such as a sickle shape. This decreases the red blood cells flexibility.

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Q: What is the illness sickle cell anemia?
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Related questions

How do you ge sickle cell anemia?

You get Sickle-Cell Anemia by Birth,it is a genetic disorder.


Is sickle cell anemia a point mutation?

An example of point-mutation is sickle-cell anemia. Sickle-cell disease is hereditary.


Can a normal homozygous individual produce offspring with sickle-cell anemia?

A normal homozygous individual can't produce offspring with sickle cell anemia. Both parents must carry the trait to have an offspring with the illness.


Is Sickle cell anemia genetic?

Yes, Sickle Cell Anemia is in fact a genetic disorder.


Is sickle cell anemia recessive or dominant?

Sickle cell anemia is an autosomal recessive disease. Carriers have sickle cell trait, which confers resistance to malaria.


Sickle-cell anemia is an example of a point-mutation?

An example of point-mutation is sickle-cell anemia. Sickle-cell disease is hereditary.


What is a genetic autoimmune difficiency in which blood cells look like a sickle It is not sickle cell anemia?

sickle cell anemia


Is sickle cells disease hereditary?

Sickle cell anemia -yes it is hereditary


When was sickle cell anemia discovered?

Sickle cell anemia was discovered in the 1870's and carried many names, but 1922 it was officially named sickle cell anemia.


Which form of anemia is a genetic disorder?

It sounds like you are looking for Sickle Cell Anemia.


Is sickle cell anemia genetic or environmental?

Sickle cell anemia is genetic. It is an autosomal recessive disease.


Is sickle cell anemia a type of poikilocytosis?

Yes, drepanocytosis(sickle cell anemia) is a type of poikilocytosis.