Stiff person syndrome (SPS) is an extremely rare progressive neurological disorder characterized by persistent rigidity and spasms of certain voluntary muscles, especially those of legs and feet.
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The cause of stiff person syndrome is unknown, however, researchers theorize that SPS may be an autoimmune disorder.
"Stiff Man Syndrome" now usually called "Stiff Person Syndrome" is a rare disease of the nervous system that causes progressively severe muscle stiffness in the spine and legs. It is thought to be caused by an autoimmune disorder, where the enzyme responsible for making certain neurotransmitters is destroyed by the immune system. Stiff person syndrome is very rare, so it is difficult to determine the exact prevalence of the disease. However, estimates are about 1 in 1 million people will get this disease. It is more common in diabetics, about 1 in 10 thousand people with diabetes will be affected.
There is no cure for SPS and the long-term prognosis is variable. Many patients have a slow course of the disorder that is mostly without symptoms, punctuated by occasional episodes of stiffness.
Sjogren-Larsson syndrome is an inherited condition resulting in thickened, dry, rough skin (ichthyosis), mental retardation , and stiff, rigid muscles (spasticity ).
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Carpel tunnel syndrome causes a wrist and hand to be stiff and sore. Tendonitis of the wrist, sprains, and arthritis can also cause a hand and wrist to swell, be sore, and stiff.
The word stiff is usually an adjective, so would have no plural. The colloquial noun "stiff" (a corpse, or a boring person) would have the plural "stiffs."
A person with Klinefelter's syndrome possesses an extra X chromosome.
An asperger is an informal term for a person who has Asperger's syndrome.
Cardiac amyloidosis or "stiff heart syndrome" is a disorder that is caused by abnormal protein deposits in the heart tissue, making it difficult for the heart to function properly. Symptoms include excessive urination, fatigue, shortness of breath, swelling of the abdomen and heart palpitations.