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Trepanning was used during the Prehistoric period to remove evil spirits that cause inner pain and diseases. Trepanning was also used in Ancient Egypt and Greece
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The large opening at the base of the skull is called the foramen magnum. It allows the spinal cord to pass through and connect to the brain.
Ancient cave peoples treated Migraine with a procedure called Trepanning.
Trepanning
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Skulls from primitive man have been found with holes bored in them for brain surgery (called trepanning)
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Trepanning or trephining, in which the surgeon drilled a hole as large as 1-2 in diameter in the patient's skull without benefit of anesthesia.
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