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What is a pro-drug?
A pro-drug is a pharmacological inactive compound which becomes active through metabolism.
When was Drug Metabolism Reviews created?
Drug Metabolism Reviews was created in 1972.
What are the three phases of drug effects?
Pharmacokinetic phase: involves the absorption, distribution, metabolism, and elimination of the drug in the body. Pharmacodynamic phase: refers to the drug's interaction with its target receptors and the subsequent biochemical and physiological effects. Phase of termination: marks the decline of drug effects as the body clears the drug through metabolism and excretion.
What the use of vasteral?
Trimetazidine. A metabolic drug intefering and improving heart muscle oxygenation through better glucose metabolism and decrease fatty acid metabolism. Serve as an anti anginal. Can be added to nitrates therapy. No major side effects other than GI discomfort.
Where does drug metabolism occur?
Drug metabolism primarily occurs in the liver, where enzymes break down drugs into metabolites that can be excreted from the body. Other organs, such as the kidneys and intestines, also play a role in drug metabolism to some extent.
What drug speeds up your metabolism?
The drug that you use!~
What drugs slow drug metabolism?
Drugs that slow drug metabolism include ciprofloxacin, erythromycin, fluoxetine, nefazodone, paroxetine, and ritonavir
What factors determine a drug's rate of metabolism?
How quickly a drug clears from the body is a function of its absorption, bioavailability, distribution, metabolism, and excretion properties.
The process by which alcohol leaves the body?
Alcohol leaves the body through metabolism, respiration, urination, and perspiration.
What is the difference between first pass and phase one of drug metabolism?
First pass metabolism refers to the metabolism of a drug that occurs in the liver after it is absorbed from the gastrointestinal tract, before it enters systemic circulation. Phase 1 metabolism is the initial biotransformation of a drug, primarily carried out by enzymes such as cytochrome P450, to make the drug more polar and easier to eliminate from the body.
What speeds up your metabolism?
The drug that you use!~
What are the parts of the pharmacokinetic process?
The pharmacokinetic process consists of four main parts: absorption, distribution, metabolism, and excretion. Absorption refers to the process by which a drug enters the bloodstream, distribution describes how the drug spreads throughout the body tissues, metabolism involves the biochemical modification of the drug, primarily in the liver, and excretion is the elimination of the drug from the body, primarily through the kidneys. Together, these processes determine the drug's bioavailability, efficacy, and duration of action.
