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Each antibody has a variable region at the top of the arms of the Y-Shaped structure of the antibody. These variable regions each have a different sequence of amino acids and therefore a different structure. This means that only specific antigens can bind to the binding sites - only those with a complementary shape. The antigen fits into the binding site by induced fit. Once the antigen has bound to the antibody it forms a highly specific antigen-antibody complex. Therefore the role of the variable region is to produce a specific binding site for each type of antigen.
Wiki User
∙ 14y ago
Wiki User
∙ 12y ago· The constant region that form the stem of the antibody monomer determine that antibody class and serve common functions in primarily in body secretions, some cross the placental barrier and so on.
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