"Best" is extremely subjective and depends on many factors and opinions. A large caliber rifle is a formidable weapon, but it isn't normally what people refer to as a hand-held weapon, even though it's held in your hands. A large caliber handgun is a fairly formidable weapon. A knife can be an extremely formidable weapon under the right circumstances. A knife never jams or runs out of ammo, but a handgun gives you (generally speaking) more range. In order to say what is "best" we would need to know several things. How/where/when will it be used? What is legal where you are? and any other information you can give us about why you need it.
Patience
Man.
The best weapon was the German mg42. It was so good that it is still in service in parts of the world today. It has an immense rate of fire.
Hand cuffs.
any weapon just enchance and you'll be good
The Garmin GPS is one of the top rated handheld gps products available. They are known as the best GPS in the world. They fit any activity that you have in mind.
Atomic bomb.
syntechome
During World War II, the 'best' weapon that was designed, constructed, and utilized, when measured in terms of overall power, was the atomic bomb. Through the effective (if also regrettable) use of this weapon, the world-wide conflict was finally brought to a conclusive end in August of 1945.
the best weapon ever used in ww1 is the machine gun because it stabelized the front and cuased massive losses on both side
A boffer is another name for a foam weapon, something shaped like a weapon but made out of foam in order to participate in simulated handheld combat. Boffers are used a lot in live acting role playing.
A gun is any kind of fire arm from a small handheld weapon up to a large cannon. A revolver is usually a handheld weapon. It holds more than one cartridge containing powder and bullet in a magazine that is part of the weapon. Each cartridge in aligned in turn with the firing pin and gun barrel for firing by revolvingthe cartridge magazine. Hence the name, revolver.