There is no definite best because it's up to how you like the stats. My favorite is the final boss sword, you unlock it by grabbing it right after you kill his final form.
The fastest weapon is the black mace from the skeletons, you unlock that one by getting a critical hit on a skeleton holding one, or you can just get somebody with it to drop it so you can pick it up.
In my opinion, the Spur is the best weapon in Cave Story (some people might like a different weapon better). But, if I'm not mistaken, it does the most damage.
Last prisom and the meomer and the star wraith
Either the last prism or the lunar flare (both magic weapons)
you will need a blue ghost thing that u get from toros cave and the best weapon is a long sword
That all depends on what type of weapon you use, but from what I've seen, the VIP weapons seem to be the best.
A legendary weapon
the ultimate weapon was the revolver mentioned at the end of the story. Good Luck!
Cave Story was created on 2004-12-20.
Go to crystal cave, finish the quest, and they give a light weapon.
The ISBN of Weapon X - story arc - is 978-0785137269.
the brilliant blinding light of destiny or if you dont have a d.a. go to warlic and do the crystal cave quest to get a good light weapon cuz the destiny weapons are expensive and time consuming to cultivate
Probably as a weapon to be thrown, or as a cave shelter.
Cave Story takes place in the floating island of Mimiga at an unspecified time. The exact time period is not specified in the game.
The Whipper is the best weapon for Wyplash.
There's no such thing as the best weapon. You can only define the best weapon for a already given situation. The best weapon is the one that allow you to utilize your army as a whole. But one weapon is never enough.