The building up phase of metabolism is called
The building up phase of metabolism is called
There are two phases of drug metabolism: Phase I - Functionalizes the drug molecule. In this phase, there are addition or modification of functional groups in order to make them more susceptible to phase II of metabolism. Phase II - Conjugates the molecule. In this phase, the functional handles of the molecule can be conjugated to highly hydrophilic molecules in order to facilitate the excretion.
Pharmacokinetic phase: involves the absorption, distribution, metabolism, and elimination of the drug in the body. Pharmacodynamic phase: refers to the drug's interaction with its target receptors and the subsequent biochemical and physiological effects. Phase of termination: marks the decline of drug effects as the body clears the drug through metabolism and excretion.
Glycolysis is the break-down phase.
The phase of the cell cycle that involves cell growth, normal metabolism, and DNA replication is known as the S phase. This is when DNA synthesis occurs, resulting in the duplication of the cell's genetic material. After the S phase, the cell enters the G2 phase, where it prepares for cell division.
Anabolism is the phase of metabolism that is responsible for growth and repair of tissues in the body. It involves building larger molecules from smaller ones and requires energy input.
First pass metabolism refers to the metabolism of a drug that occurs in the liver after it is absorbed from the gastrointestinal tract, before it enters systemic circulation. Phase 1 metabolism is the initial biotransformation of a drug, primarily carried out by enzymes such as cytochrome P450, to make the drug more polar and easier to eliminate from the body.
The end product of the anaerobic phase of glucose metabolism is lactate (lactic acid). This process occurs in the absence of oxygen when energy needs are high.
catabolism
Cytochrome P450 allows amphetamine to undergo oxidative deamination.
Cytochrome P450 allows phenobarbitual to undergo aliphatic hydroxylation. It then turns into an alcohol.
The chemical alteration of drug or substance in the presence of various enzymes that acts as a catalyst and themselves not consumed in a chemical reaction and there by may activate or deactivate the drug is called metabolism. Metabolism in Pharmacokinetics refers to the Phase I and Phase II continuation reactions that modify the parent drug compound into a inactive compound or metabolite. In rare instances, Phase I or Phase II reactions produce a more active compound than the parent compound which can lead higher chances of toxicity in patients. Metabolism makes the drug inactive while making it more hydrophilic through modification of the side chains of the chemical compound so it is easier to be excreted from the body.