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The changes in the BIS algorithm resulting from updating and refinement of the producer's database make it difficult to compare results obtained by different investigators using different versions of the BIS monitor.

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How was a database for the bispectral index compiled?

researchers recorded EEGs from several thousand patients and volunteers anesthetized with a range of commonly used anesthetics and anesthetic combinations.


What is the bispectral index?

one of several systems used in anesthesiology as of 2003 to measure the effects of specific anesthetic drugs on the brain and to track changes in the patient's level of sedation or hypnosis


What benefits has the bispectral index brought?

BIS reduces the risk of patient awareness during surgery as well as lowering hospital costs by speeding patient recovery and reducing the overuse of anesthetic agents.


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What anesthesia monitoring systems besides bispectral index are in use?

the Patient State Analyzer, or PSA 4000, which is also based on EEG data; and the A-Line (R) monitor, which processes signals derived from auditory stimuli.


How does bispectral analysis use data obtained by electroencephalogram?

Bispectral analysis is a method of analyzing the mathematical relationships among the various components of an EEG signal (phase couplings) as well as measuring amplitudes and frequencies.


What is the practical application of the bispectral index?

The BIS system displays both raw data from the EEG and a single number between 100 (indicating an awake patient) and 0 (indicating the absence of brain activity) that represents the patient's degree of sedation.


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