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Q: What is the clinical significance of rouleaux formation?
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What causes rouleaux formation?

The red blood cells stack up like coins. http://en.wikipedia.org/wiki/Rouleaux


How is rouleaux formation differentiated from true agglutination?

Autoagglutination should also be distinguished from "Rouleaux formation" wherein normal blood tends to form stacks on keeping, which disperses on dilution with normal saline.


What is mean by RBC's form rouleaux?

Rouleaux refers to the stacking of red blood cells (erythrocytes) in human blood. Rouleaux formation is enhanced in the presence of increased plasma proteins, leading to an increased erythrocyte sedimentation rate (ESR).


Why rouleaux formation does not occur in vivo?

When rouleaux formation is truly present, it is caused by an increase in cathodal proteins, such as immunoglobulins and fibrinogen.And the fibrinogen is not present in blood in vivo*This is not true. Fibrinogen is secreted by liver and is present in blood. The reason rouleaux do not form in vivo is that they only form under low shear stress conditions. With blood flow, the cross-sectional fluid velocity gradient in the blood vessel results in shear stress levels that exceed the threshold for rouleaux formation.


What medical conditions are related to rouleaux formation of the red blood cells?

Multiple Myeloma


What is rouleaux formation?

Rouleaux formation occurs when red blood cells form rolls or stacks. If not due to an artifact, such as a result of not preparing the blood smear soon enough after placing the blood on the slide, it may be due to the presence of high concentrations of abnormal globulins or fibrinogen. This formation is found in multiple myeloma and macroglobulinemia.


Clinical significance of pleural recess?

clinical importance of pleural recess


What is roulex formation?

This question probably is spelled wrong (roulex). A rouleaux formation is: A stacklike arrangement of red blood cells in blood or in diluted suspensions of blood in which their biconcave surfaces are next to each other.


What is the clinical significance of calcification?

There is a great clinical significance of calcification. Calcification can lead to things like kidney stones that are very painful.


Clinical significance in the treatment of homoeopathy?

koi to do iska answer


What is cortical thickening on femur?

Clinical significance of cortical thickening of the femur


What is the difference between clinical significance and statistical significance?

look for a paper being published in "The Oncologist" later this year (2008)