What is the difference between Fentanyl and oxycodone?

Fentanyl is normally primarily used as a general anesthetic, where Oxycodone is an acute pain medication. However, when prescribed as a chronic pain med, Fentanyl Transdermal Patches are typically the opiate therapy of last resort for severe chronic pain patients, who have used all other lesser forms of opiates without long term success, their opiate tolerance has exceeded acute pain med limits, or their pain requires 24/7 relief. Most acute meds like Oxycodone only last 4-6 hours; the longest lasting timed-release version of Oxycodone (OxyContin) at best last 12 hours. Fentanyl patches last anywhere from 48-72 hours depending on the patient and their opiate tolerance level.

The biggest difference of course is strength; Fentanyl is the strongest opiate on the planet, and is 100x stronger than morphine.