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Integration
Integration
The type of neurotransmitter.
When neurotransmitters communicate an inhibitory message to the postsynaptic neuron:
The neuron adds up all the excitatory and inhibitory inputs and fires when they reach its threshold of excitation.
Neurons integrate incoming signals and sum up the excitatory and inhibitory signals, integration. The excitatory neurotransmitter produces a potential change (signal). This signal pushes the neuron closer to an action potential. If the neuron receives excitatory signals chances are that the axon will transmit a nerve impulse. The inhibitory neurotransmitter produces signals that drive neurons further from an action potential. If neurons receive both the inhibitory and the excitatory signals the summing of the signals may prohibit the axon from firing.
Inhibitory neurotransmitters prevent the firing of neurons by binding with certain receptors, causing the influx of chloride ions to hyperpolarize the neuron. When this happens, it requires a much larger excitatory signal to override the inhibitory effects in order to allow the neuron to fire.
The process by which inhibitory and excitatory post-synaptic potentials summate and control the rate of firing of a neuron.
All neurotransmitters have an effect on the post synaptic membrane of either inhibition or excitation. Dopamine is an Excitatory NT so if a Excitatory Neuron meets with another Excitatory Neuron it creates Excitation. However if it meets with an Inhibitory Neuron Dopamine and the other Excitatory NT's wll only create Inhibition. Only GABA and Glycine are considered Inhhibitory NTransmitters.
Probably because some portion of those synapses are inhibitory as opposed to excitatory.
It sends an impulse back to the cell body of the neuron
As a rule more than one presynaptic action potential is needed to fire the postsynaptic neuron or muscle so that the trigger to initiate an action potential are either many subthreshold local potentials from different sources or from the same neuron received within a short period of time. The first case is called spatial summation and the second case is called temporal summation. Whether a postsynaptic potential (another term for a local potential) is excitatory or inhibitory depends on what ion channels are affected by the transmitter released from the presynaptic vesicles.