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vicodin is an opiod narcotic painkiller semisynthetically derived from thebaine, an alkaloid of the opium poppy, and promethazine is a phenothiazine tranq. Non narcotic. Huge difference, like the difference between benadryl and Diet Coke. phenagren can cause seizures.

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Q: What is the difference between vincodin and promethazine?
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