What is the distance between Irvine and Phoenix Arizona?

Answer 1

355 miles taking this route:

1. Follow the EASTERN TRANSPORTATION CORRIDOR from Irvine, which consists of taking CA-133 TOLL ROAD - NORTH or CA-261 (toll road) - NORTH, from Irvine to CA-241 TOLL ROAD - NORTH towards RIVERSIDE (EXIT 14B off CA-133 - EXIT 6B off CA-261); then continue on CA-241 TOLL ROAD - NORTH to CA-91 EAST to RIVERSIDE at EXIT 39A. (OR, if you want to avoid tolls, take I-5 NORTH from Irvine, to CA-55 NORTH (Costa Mesa Fwy) to RIVERSIDE at EXIT 103A; then take CA-55 NORTH to CA-91 EAST to RIVERSIDE at EXIT 18A.)
2. Take CA-91 EAST to CA-60 EAST to INDIO at EXIT 65B, in Riverside.
3. Take CA-60 EAST to I-10 EAST to INDIO.
4. Take I-10 EAST to Phoenix.