What is the distance between Macon GA and Palatka Fl?

Answer 1

314 miles taking this route:

1. Take I-75 SOUTH from Macon to I-10 to JACKSONVILLE and TALLAHASSEE off EXIT 435 in Florida. Follow signs to I-10 EAST to JACKSONVILLE.
2. Take I-10 EAST to I-295 off EXIT 356. Follow signs to I-295 SOUTH to ST. AUGUSTINE.
3. Take I-295, around JACKSONVILLE, to U.S. 17 off EXIT 10. Turn right off the exit ramp onto U.S. 17 SOUTH.
4. Take U.S. 17 SOUTH to Palatka.