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Three major cities in New York State are: New York City, Syracuse, and Buffalo.
Syracuse, Rochester, Buffalo
Buffalo, NY is the westernmost city on the Erie Canal.
New York, Buffalo, Rochester, Yonkers, and Syracuse.
Lake effects
The five largest cities in New York in order are New York City, Buffalo, Rochester, Yonkers, and Syracuse
In terms of actual cities, it would be Syracuse, Buffalo, and Rochester in that order.
New York City, Buffalo, Rochester, Yonkers, Syracuse.
Lake effect
Rochester NY is approximately 115 miles northwest of Utica NY. The driving distance between the two cities is about 2 hours.
New York, Albany, Rochester, Buffalo, Syracuse
The distance between the two cities' major airports is about 1,993 air miles.