327 miles
San Diego, California
The driving distance is 332 miles per Map Quest. The driving time from San Diego to Las Vegas per Map Quest is 5 hours and 15 minutes.
Las Vegas is farther west
375
The highway
about 5 hours
Las Vegas and San diego
5 - 6 hours
The driving distance from San Francisco, CA, to Las Vegas, NV, is 568mi / 914km
Los Angeles to Las Vegas
It is farther to San Francisco from Los Angeles then is the drive to Las Vegas.