This Depends on the rush
The shortest driving time is 1 hour and 48 minutes.
Google Maps estimates the driving time as 2 hours and 50 minutes.
The driving time between Newbern, Tennessee and Knoxville, Tennessee is 5 hours 35 minutes. The driving distance is 357.8 miles.
The driving distance between Knoxville, TN and Germantown, TN is approximately 380 miles. The driving time would be approximately 6 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
About 7.5 hours.
The driving distance between Knoxville, TN and Nashville, TN is approximately 180 miles. The driving time would be approximately 3 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
The driving distance between Knoxville, TN and Smyrna, TN is approximately 175 miles. The driving time would be approximately 3 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
The driving distance between Knoxville, TN and Nashville, TN is approximately 180 miles. The driving time would be approximately 3 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
The distance between Reidsville, NC and Knoxville, TN is 297 miles and will take about 5 Hours of driving time.
The driving distance between Knoxville, TN and Hixson, TN is approximately 110 miles. The driving time would be approximately 1 hours 45 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
The driving distance between Knoxville, TN and Kingsport, TN is approximately 100 miles. The driving time would be approximately 1 hour 45 minutes if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)
The driving distance between Knoxville, TN and Elizabethton, TN is approximately 115 miles. The driving time would be approximately 2 hours if you were to travel non-stop in good driving conditions. (The driving time does not take into consideration conditions which may extend trip time such as weather, road work and rush hour traffic in urban areas.)