That would depend a great deal on where you're coming from.
Santa Fe, NM about 19.5 hours Santa Fe, TX about 6.25 hours
From Tampa, FL to Santa Fe, NM is 1,904 miles; approximately 29 hours driving time.
The driving distance from Prescott, Arizona to Santa Fe, New Mexico is 478 miles via I-40 E per MapQuest. The driving time per MapQuest is 7 hours.
The route with the shortest driving time is about 360 miles.
The driving distance from Austin, TX to Santa Fe, NM is 690 miles.
The driving distance from Santa Fe, NM to Ottawa, KS is 708 miles.
The driving distance between Seattle, WA and Santa Fe, NM is 1724 miles. The driving time would be approximately 27 hours if driving non-stop in good conditions. (The driving time does not take into consideration conditions such as weather, road work and rush hour traffic in urban areas.)
The driving distance from Santa Fe NM to Boulder CO is 422 miles per Map Quest. The driving time per Map Quest is 6 hours and 15 minutes.
MapQuest estimates the driving time as 7 hours and 24 minutes.
MapQuest estimates the driving time as 10 hours.
Google Maps estimates the driving time as 6 hours and 23 minutes.
Given is the calculated distance as well as the driving travel time, which does not take into account driving conditions, traffic, etc. The distance between Deming, New Mexico and Santa Fe, New Mexico is 295 miles. The resulting travel time is 4 hours and 51 minutes.