wheel
the first instrument made was the harmonica the first instrument made by man was 60,000 years old ,which was a flute, but really the first instrument was the human voice because anything that produces sound can be served as a musical instrument The human voice! well it was kinda the birds voice because the sing to.
Seismagraph
scalpel
telescope
The sun.
Glockenspiel :)
Evolution and/or God, depending upon your perspective. A set of vocal cords was the first instrument used by humans.
Only on thursdays
I would have to say the voices of His angels.
The cast of The Instrument Man - 2009 includes: Alexis Jacquin as Instrument Man Christina Thodos as Maureen Chapman
Drums.
Zither