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Both syndrome's indicate the presence of a 47th chromosome (or extra part of a chromosome). Most humans have 23 pairs of chromosomes, totaling 46 chromosomes.

For Down's syndrome, the 47th chromosome appears with the 21st pairing. For Klinefelter's syndrome the 47th chromosome appears with the 26th pairing (the gender chromosomes.)

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13y ago
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12y ago

Klinefelter syndrome is when a man is born with an additional X chromosome. Therefore, he is XXY.

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8y ago

the disease would be caused by the presence of all or part of an extra 21st chromosome.

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13y ago

what is the genetic connection's in down's syndrome

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11y ago

Both are non-disjunctions and chromosomal abnormalities

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Q: What is the genetic cause of Down syndrome?
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