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This info is from the University of Maryland Medical Center:
I believe this info is just for inhaled NAC, if anybody knows whether the half life is the same for inhaled versus injected NAC, that would be greatly appreciated.

Pharmacodynamics/Kinetics:

Onset of action: Inhalation: 5-10 minutes

Duration: Inhalation: >1 hour

Distribution: 0.47 L/kg

Protein binding, plasma: 83%

Half-life elimination:

Reduced acetylcysteine: 2 hours

Total acetylcysteine: Adults: 5.5 hours; Newborns: 11 hours

Time to peak, plasma: Oral: 1-2 hours

Excretion: Urine

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