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The halfway point between Alexandria, LA and Joplin, Missouri is Nutts, Arkansas (yes, really).
The halfway point between Lafayette, Georgia and Clinton, Missouri, falls in Charleston, Missouri.
The halfway point between Mt. Pleasant, Iowa, and Branson, Missouri, is about halfway between Fulton and Jefferson City, Missouri.
That would place you in the area of Wets Plains, Missouri - according to Google Earth.
Hicoria, Florida is the halfway point between Largo, Florida and Boca Raton, Florida. There is approximately 251 miles between Largo and Boca Raton.
West Plains, Missouri is halfway between Tulsa and Clarksville
Cave, Missouri is halfway between Fayetteville & Chicago
There is approximately 106 miles between Orlando, Florida and Clear water, Florida. The halfway point between these two cities is Lakeland, Florida.
The halfway point between Monticello, IA and Springfield, MO falls in or around Perry, Missouri.
Dawsonville, Missouri is your halfway point.
Culiver, Missouri is halfway between Greenwood & Apple Valley
The halfway point between Davie, Florida and Jupiter, Florida is Delray Beach, Florida.