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Your spleen's main function is to act as a filter for your blood. It recognizes and removes old, malformed, or damaged red blood cells. When blood flows into your spleen, your spleen performs "quality control"; your red blood cells must pass through a maze of narrow passages. Healthy blood cells simply pass through the spleen and continue to circulate throughout your bloodstream. Blood cells that can't pass the test will be broken down in your spleen by macrophages. Macrophages are large white blood cells that specialize in destroying these unhealthy red blood cells.
Always economical, your spleen saves any useful components from the old cells, such as iron. It stores iron in the form of ferritin or bilirubin, and eventually returns the iron to your bone marrow, where hemoglobin is made. Hemoglobin is an important protein in your blood that transports oxygen from your lungs to all the parts of your body that need it.
Another useful thing your spleen can do is store blood. The blood vessels in human spleens are able to get wider or narrower, depending on your body's needs. When vessels are expanded, your spleen can actually hold up to a cup of reserve blood. If for any reason you need some extra blood – for example, if trauma causes you to lose blood – your spleen can respond by releasing that reserve blood back into your system.
Your spleen also plays an important part in your immune system, which helps your body fight infection. Just as it detects faulty red blood cells, your spleen can pick out any unwelcome micro-organisms (like bacteria or viruses) in your blood.
When one of these invaders is detected in your bloodstream, your spleen, along with your lymph nodes, jumps to action and creates an army of defender cells called lymphocytes. Lymphocytes are a type of white blood cell that produces antibodies, special proteins that weaken or kill bacteria, viruses, and other organisms that cause infection. Antibodies and white blood cells also stop infections from spreading through the body by trapping germs and destroying them.
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the most unknown organ in the human body is the spleen
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