A condition produced by the excessive or long-continued use of quinine, and marked by deafness, roaring in the ears, vertigo, etc.
Quinine. (Too much quinine in one's system can lead to cinchonism.)
Chloroquine is considered superior to quinine primarily due to its improved efficacy, safety profile, and tolerability. Chloroquine has a more favorable pharmacokinetic profile, allowing for easier dosing and better absorption. Additionally, it has fewer side effects and is generally better tolerated by patients compared to quinine, which can cause more severe adverse reactions such as cinchonism. Consequently, chloroquine has become the preferred treatment for certain types of malaria.
Taking too much quinine can lead to serious side effects, including tinnitus (ringing in the ears), headache, nausea, and abdominal pain. In severe cases, it can cause more dangerous conditions such as cinchonism, which includes symptoms like visual disturbances and cardiac arrhythmias. Overdose can also lead to hemolytic anemia and other complications. If an overdose is suspected, it's important to seek medical attention immediately.
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Chloroquine and primaquine are antimalarial medications used to treat and prevent malaria. Chloroquine primarily targets the blood stages of the malaria parasite, while primaquine is effective against the liver stages and helps prevent relapses. Quinine, derived from cinchona bark, is used for treating severe malaria and can cause side effects such as cinchonism, which includes symptoms like tinnitus, headache, and nausea. Together, these medications can effectively combat malaria but may have varying side effects and resistance issues.
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