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Glacial acetic acid is a trivial name for water-free (anhydrous) acetic acid
As a general term, a substance is said to be anhydrous if it contains no water.
Glacial acetic acid is an excellent polar protic solvent, as noted above. It is frequently used as a solvent for recrystallization to purify organic compounds.
Acetic acid is often used as a solvent for reactions involving carbocations, such as Friedel-Crafts alkylation; here acetic acid acts both as a solvent and as a nucleophile to trap the rearranged carbocation.
run in a glacial acetic acid in order to dissolve the starting materials
Glacial acetic acid (pure anhydrous acetic acid) is used as the reaction solvent, but it also plays an important role as an acid catalyst. Note that the halogenation reaction requires the reactant ketone be tautomerized to the enol form, which occurs under acid catalysis (base catalysis on the other hand would yield the corresponding enolate anion). So as the Br2 consumes the enol form by reacting with it, more enol will need to be generated and the acetic acid increases the rate at which this happens, thereby accelerating the overall reaction. The tautomerization mechanism involves simply protonation of the carbonyl oxygen of the ketone followed by deprotonation of its alpha carbon (carbon adjacent to the carbonyl carbon), with replacement of the CO double bond with a single bond and the formation of a double bond between the carbonyl carbon and the alpha carbon.
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Mechanism of azo dye Para Red synthesis?
Azo food dyes don't set off allergic reactions as such, though some azo textile dyes can cause your skin to be hypersensitive. The mechanism for why tartrazine increases allergic reactions is not yet known.
What is use of p-bromoacetanilide?
Antipyretic and Analgesic
What do we call each step that makes up a reaction mechanism?
Each step in a reaction mechanism is referred to as an elementary step.
Can a reaction mechanism be determined without an experiment?
A reaction mechanism can be proposed using computational studies. But needs to be experimentally proved.
Is HCl(aq) C2H4(aq)C2H5Cl(aq) considered a reaction mechanism?
No, HCl(aq) C2H4(aq)C2H5Cl(aq) is not considered a reaction mechanism. It appears to be a chemical equation representing a single-step reaction where HCl reacts with C2H4 to form C2H5Cl. A reaction mechanism involves multiple steps and intermediates, detailing the complete pathway of a chemical reaction.
Why acetanilide brominates in the ortho and para positions and the amount of o-bromoacetanilide?
The polarization of bromine in bromoacetanilide reaction
Why is not recommended to obtain para -bromoacetanilide by bromination of aniline then acetylation?
Aniline is a benzene with an amine group attached to it. When you brominate aniline, since aniline is electron donating, it directs other substituents to the ortho and para positions. Therefore you will not only get para-bromoacetanilide. However if you just want para-bromoacetanilide, you should go through acetylation first because this changes the amine group on the aniline into an acetamido group which is very bulky and big, and also electron donating. Since it is so big, the bromine cant attach to the ortho positions because of the steric hindrance caused by the very bulky acetamido group and therefore you will get para-bromoacetanilide as your product.
What are the uses of para-bromoacetanilide?
it is used in the syntesis of organic compound
Mechanism of azo dye Para Red synthesis?
Azo food dyes don't set off allergic reactions as such, though some azo textile dyes can cause your skin to be hypersensitive. The mechanism for why tartrazine increases allergic reactions is not yet known.
Why is only 4-bromoacetanilide created mainly from a bromination of acetanilide?
The Acetanilide is a benzene with a acetamido group attached to it. The acetamido group is electron donating and therefore it directs other substituents to the ortho and para positions. The acetamido group is also a very large group and the ortho position is right besides the acetamido group. This creates steric hindrance from bromine from getting to the ortho position and therefore only para-bromoacetanilide or 4-bromoacetanilide is created mainly from a bromination of acetanilide.
How can reaction be classified?
mechanism. mechanism.
What is the balanced equation for the production of benzocaine from PABA aka para-aminobenzoic acid and ethanol?
PABA +ethanol --> benzocaineAcid is used as a catylsis in this reaction and the mechanism is Fischer Esterification
What is reaction mechanism of uric acid and ascorbic acid?
give structure of reaction mechanism of uric acid
What is the mechanism for the aldol condesation reaction of acetone and p-anisaldehyde?
Write a reaction mechanism for cinnamaldehyde and acetone
What is the mechanism of reaction between Wagner's reagent and alkaloids?
what is the reaction mechanism between wagner's reagent and alkaloids
What is 4 Bromoacetanilide used for?
analgesic and antipyretic
What is use of p-bromoacetanilide?
Antipyretic and Analgesic
