Hello,
McPherson published the crystal strcuture of an antibody-antibody interaction and as far as I can understand the explanations, the total size of the complex is approx. 15 nm in length. If you assume that the interaction is nearly planar, one can assume for a single antibody an approx. length of 7.5 nm. But please check the link below with the original article...
http://www.pubmedcentral.nih.gov/picrender.fcgi?artid=43211&blobtype=pdf
Jonathan M. Austyn has written: 'Principles of cellular and molecular immunology' -- subject(s): Cellular Immunity, Immunity, Molecular biology, Molecular immunology 'Antigen-presenting cells' -- subject(s): Antigen presenting cells, Antigen-Presenting Cells, Immunology
An Immunogen is foreign particle that triggers the body's immune system where as Antigen is also a foreign particle , due to its low molecular weight it is unable to trigger immune system. Example for antigen is Hapten
An antigen has to be a protein or molecule of a certain and complex size. NaCl, table salt, is not large enough of a molecule to be an antigen.
No. Hapten is an antigen whic has low molecular weight and does not trigger immune system.
mention factors affecting antigenicity 1) molecular weight of antigen. e.g. protein is a good antigen as compare to lipid or nucleic acid. 2) invecivness of antigen, that is due to toxins or chemicals secreted by the antigen 3) degredibility: antigen should be degreted in body so that body immune system can react against them. 4) complexicity of antigen
Not if they are dissolved - if they are then they're of molecular size.
if the antigen is more foreign , then the immunogenicity is high if the immune response is high, then the immunogenicity is also high Immunogenicity of Antigens : •Determined by -Foreignness -Molecular Size -Chemical Composition -Degradability •Influenced by -Host genotype -Dose and route of administration -Presence of adjuvants
Pamela Sumiko Ohashi has written: 'Molecular analysis and expression of T cell antigen receptor genes'
You think probable to the separation with molecular sieves.
molecular exclusion chromatography is the exclusion or separation of protein particles based on their molecular size. Bhubanyu Basu
A antigen
gasses take up the entire volume of their containers regardless of their molecular size. The intermolecular space is so huge that their molecular mass is negligible in comparison.