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cortisol

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13y ago

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What hormone is released from the pancreas and generally increases the rate of gluconeogenesis in the liver?

glucagon


What hormone causes gluconeogenesis in the liver?

Glucagon is the hormone that stimulates gluconeogenesis in the liver by increasing the breakdown of glycogen into glucose, promoting the formation of new glucose molecules.


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The hormone that fits this description is cortisol. Cortisol is a stress hormone that promotes the breakdown of proteins into amino acids to increase fatty acid release and stimulate gluconeogenesis (glucose synthesis) in the liver.


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Is gluconeogenesis the prime metabolic effect of cortisol?

Yes, gluconeogenesis is considered one of the primary metabolic effects of cortisol. Cortisol, a glucocorticoid hormone secreted by the adrenal cortex, plays a key role in maintaining blood glucose levels, especially during fasting or stress. Its main metabolic action is to stimulate gluconeogenesis, which is the production of glucose from non-carbohydrate sources like amino acids and glycerol in the liver. Other important metabolic effects of cortisol include: Protein catabolism: Breakdown of muscle proteins to provide amino acids for gluconeogenesis Lipolysis: Mobilization of fat stores for energy Inhibition of peripheral glucose uptake: Acts as an anti-insulin hormone, reducing glucose uptake in muscle and adipose tissue Promotion of glycogen synthesis in the liver despite its hyperglycemic effect While cortisol has multiple metabolic actions, gluconeogenesis is considered its hallmark effect, particularly during periods of physiological stress or starvation.


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