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Highway 50 is a good route to choice.
It depends on your route, but the approximate driving distance (using major roadways) is 440 miles.
The driving distance from Lexington, KY to Destin, FL is approximately 600 miles, which would take around 9-10 hours depending on traffic and route chosen.
Check Mapquest.com
It is 433 miles and 7 hours and 12 minutes of driving time by the fastest (but not the shortest) route according to Google Maps.
It is 714 mles via the fastest (but not the shortest) route according to Google Maps.
The Scenic Route - 2008 was released on: USA: 2008
Southern Scenic Route was created on 1988-11-06.
14 hrs 6 minutes actual driving on the route recommended by our friends at Google Maps.
The driving distance between Destin, FL and Oxford, MS is approximately 400 miles, depending on the specific route taken. It would take around 6 to 7 hours to drive between the two locations without factoring in traffic and other potential delays.
25 South to Raton, NM 87 East to Dumas, TX 287 South into Dallas About 13-14 hours driving time.
The cast of The Scenic Route - 2009 includes: Jay Simon