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Basically all the reacitons in living systems are thermodynamic. Some of thems are exergonic which liberate heat energy and some are endergonic which utilize heat energy. Same type of reactions utilize or liberate same amount of heat energy. This energy will be constant for a particular reaction. The amount of heat liberated by same type of reactions in any microbial culture will be directly proportional to the number of microbes. So by finding the amount of heat energy produced or utilized by any microbial culture one can estimate the number of microbes present in that culture. This is the principle behind microbial calorimetry. S.Manu. Lecturer, MVJ College of Engineering, Bangalore. The number of microbes may not be accurate but it will be in the range. It depends on different aciviteis of the microbes and the growth phase of the microbes. They liberate different amonut of heat in different phases. So many correction factors are needed to make out correct number of microbes in a culture.
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