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What are the chances of a person having a sickle cell disease passing the disease to their offspring?
Wiki User
∙ 12y ago
If one represents a sickle cell gene thus "C" and a normal gene thus "O" then both parents are:
Mum CO
Dad CO
The possibilities for their children are therefore
CC
OO
CO
CO
in those proportion so 1in 4 will have sickle cell anaemia, 2 in 4 will be carriers (like their parents) and 1/4 will be normal.
Wiki User
∙ 13y ago
Wiki User
∙ 14y agoEveryone carries genes that are responsible for creating hemoglobin. Some people carry the defective sickle cell hemoglobin gene. If you and your partner both have this sickle cell gene, it will be passed on to your child. As a result, your child will develop sickle cell anemia. If you carry the sickle cell gene and your partner does not, your child will become a carrier of the sickle cell gene. They will not experience any sickle cell symptoms, but may be able to pass the gene along to their children. People who carry the sickle cell gene but do not have sickle cell anemia are said to have "sickle cell trait".
Wiki User
∙ 12y agoHe will have sickle cell and die a horrible death at the age of 2.
Wiki User
∙ 12y agothere's a 50% probability
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