it is a competitive inhibitor
A strong acid has a stabilized conjugate base. Oxalic acid is stronger than malonic acid because its conjugate base has much more resonance structures than malonic acid's conjugate base.
A classic example of a carboxylic acid decarboxylation occurs in the malonic ester synthesis. The malonic ester synthesis is a chemical reaction where diethyl malonate or another ester of malonic acid is alkylated at the carbon alpha (directly adjacent) to both carbonyl groups, and then converted to a substituted acetic acid. Malonic acid is another example of an acid that will decarboxylate when heated (not sure at what temperature this happens, though)The structure of malonic acid is HOOC-CH2-COOH.
Yes, it is diprotic, HOOC-CH2-COOH
Carbon Suboxide
Malonic acid has pKa values of 2.83 (pK1) and 5.69 (pK2). If malonic esters are used then on treatment with a strong base like sodium ethoxide, the methylene (-CH2-) hydrogen can be deprotonated, but I am not sure if that is possible for malonic acid as that will lead to a tri-anion.
A strong acid has a stabilized conjugate base. Oxalic acid is stronger than malonic acid because its conjugate base has much more resonance structures than malonic acid's conjugate base.
A classic example of a carboxylic acid decarboxylation occurs in the malonic ester synthesis. The malonic ester synthesis is a chemical reaction where diethyl malonate or another ester of malonic acid is alkylated at the carbon alpha (directly adjacent) to both carbonyl groups, and then converted to a substituted acetic acid. Malonic acid is another example of an acid that will decarboxylate when heated (not sure at what temperature this happens, though)The structure of malonic acid is HOOC-CH2-COOH.
Malonic acid is a competitive inhibitor of succinate dehydrogenase.
Yes, it is diprotic, HOOC-CH2-COOH
Carbon Suboxide
.0899M
Malonic acid has pKa values of 2.83 (pK1) and 5.69 (pK2). If malonic esters are used then on treatment with a strong base like sodium ethoxide, the methylene (-CH2-) hydrogen can be deprotonated, but I am not sure if that is possible for malonic acid as that will lead to a tri-anion.
Yes it is because of it's 2 ends of hydroxide which is polar.
Yes, several weak acids in it. pH is about 3.5 to 4.5. There is even an acid named by them: malonic acid (propane-di-oic acid, C3H4O4).
Caffeine can be synthesised (made artificially in a lab) by reacting dimethylurea with malonic acid.
In theory, any organic molecule with an enolic hydrogen (as in carboxylic acids, e.t.c.) can be used, it has simply been found that the malonic acid gives the most easily discernable colour changes and is just generally better for the reaction (Sorry for my lapse in scientific language there, I'm tired!). So the answer, in basics, is yes
To deduce the concentration of a unknown solution from a known solution. Acid/base titration are common.