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Well, The rarest disease is a skull disorder, which prevents bones from growing. It effects only one person, a toddler called Lewis Barnett. It is so rare it has no name.
Also, Kuru disease has been said to be the rearest disease. It is caused by eating human brains. It is also called laughing sickness.
http://www.funtrivia.com/askft/Question53984.html
What else can I help you with?
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