Endospre foming orgaism are of particular interest in the medical field because it is going to inflience the treatment of bacterial infection if the infecting pathogen is able to form spores. As you might already know, spores are formed inside the bacterial cell and are ejected into the external environment. The spores are quite tough and are able to grow into complete bacteria under the right physical conditions. Hence, killing the pathogen does not ensure the death of the spores as well. The spores can turn into bacteria later. Hence, for spore forming bacteria, the medical procedure has to be designed to get rid of the bacteria as well as the spores.
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The adjective of significance is significant.The adverb of significance is significantly.
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there was no significance.