No, you would get onto I75 a little north of Gainesville. Take I75 SB to either I4 West or I275 South, depending on where in Tampa you are heading.
It is, in general, 70 mph. Certain sections, for example the opening leg from Sault Ste. Marie, MI to St. Ignace, MI are 55 mph. Construction zones are 60 mph, or 45 mph when/where workers are present.
Its about 15-16 hours, taking I75 south to I40 east. Its located in the Smoky Mountains of Tennessee.
I75 would take you way out of your way. You would get their much quicker by taking I4.
250
The best way to go to Cheyenne, Wyoming from Atlanta, Georgia is to fly by airplane. If you are driving by car, take I75 north out of Atlanta, Georgia to Chattanooga, Tennessee, where you take I24, then I57, the I64 to St. Louis, Missouri. Then take I70 to Kansas City, Missouri, and I29 north to I80 in Nebraska. Go west on I80 to Cheyenne, Wyoming.
It depends on your method of travel
184 miles
From Miami: get into I 95 north until 595 East. Sty on until you merge into I75 North (you are really heading West) Stay in there until you see signs of Brandento (aprox 3 - 3½ hours drive)
79 miles
Exit 384 is one of them. I think that is Archer.
There is one in north Tampa. It is up by Bruce B Downs and I75, right off Commerce Palms. It is in a plaza right across from Lowe's. 6290 Commerce Palms Blvd. Tampa, FL 33647