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My guess is that it gets hydrolyzed to choline and acetic acid
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∙ 14y ago
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How is acetylcholine (ACh) removed from the synaptic cleft?
Acetylcholine is degraded by acetylcholinesterase
Where ACh lives?
Synaptic Vesicles
How does the drug Neostigmine work to increase the bodys synaptic performance?
it blocks things [such as acetylchoinesterase] that break down ach
After nervous stimulation stops ACh in the synaptic cleft is prevented from continuing stimulation of contraction by what?
acetylcholinesterase destroying the ACh
What is the Process by which ACh gets across cleft?
The transport process by which ACh is released into the synaptic cleft is called Exocytosis.
After nervous stimulation stops what prevents ACh in the synaptic cleft from continuing to stimulate contraction?
Acetylcholinesterase destroying the ACH
Why physostigmine is the antidote for atropine?
Physostigmine inhibit AchE (the enzyme that hadrolyse Ach), so Ach accumulate at synaptic cleft and banish the effect of atropine
How is neostigmine chemically used to treat myasthenia gravis?
Neostigmine is a competitive irreversible inhibitor of Acetylcholinesterase (AChE), an enzyme responsible for breaking down acetylcholine (ACh). Myasthenia gravis is caused by the body producing too little ACh receptors. As stimulating the ACh receptors is needed for nervous transmission, the nerve signals cannot be transmitted causing muscle weakness and fatigue. Neostigmine is hence used to inhibit AChE so that less ACh gets broken down. This leads to more ACh binding to the ACh receptors causing muscular contraction.
What is the name of the cell that releases the neurotransmitters?
Exocytosis. As a result of the influx of Calcium ions, the synaptic vesicles transport the neurotransmitter Ach (Acetylcholine) to the presynaptic membrane, the vesicles fuse to the membrane, and the neurotransmiffer, Ach, diffuses. Once the neurotransmitters cross the synaptic cleft, they bind to the receptors on the post synaptic membrane. Hope it helps a bit.
Which structure contains vesicles with acetylcholine?
Synaptic vesicles in the neuromuscular junction contain acetylcholine (ACh) which is the neurotransmitter for initiating muscular contractions.
Synaptic vesicles in the axon terminal of a motor neuron contain what neurotransmitter?
Synaptic vesicles store neurotransmitters to be released into the synapses. In the case of most motoneurons, this neurotransmitter is acetylcholine (ACh). The neurons that interface with the sympathetic nervous system, also technically motoneurons, release norepinephrine.
Select the option that lists the steps of normal nerve function in the correct order?
ACh is produced at the intercellular level and is stored in vesicles at nerve endings. nerve endings release ACh ACh attavhes to the receptor site at the receiving nerve ACh is broken down by AChE to prevent accumulation
