Acetycholine esterase. It breaks down Ach in the skeletal muscle endplate.
The presence of an enzyme called acetylcholinesterasethat degrades acetylcholine is what prevents an accumulation of the neurotransmitter and sustained muscle contraction. Acetylcholinesterase is an enzyme that can be found within the neuromuscular junction. Thus, when a nerve impulse causes the release of acetylcholine at the neuromuscular junction, there is a critical time in which the neurotransmitter can bind to receptors on the muscle before it is degraded.
Acetylcholinesterase is always present in the synaptic cleft of a neuromuscular junction. It is responsible for breaking down the neurotransmitter acetylcholine, allowing for the termination of the signal transmission between the neuron and the muscle cell.
Acetylcholine is the primary chemical transmitter released at the neuromuscular junction. It binds to acetylcholine receptors on the muscle cell membrane, leading to muscle contraction.
Acetylcholine is the chemical that transmits signals across the neuromuscular junction. It binds to receptors on the muscle cell membrane, leading to muscle contraction.
Acetylcholine is the primary neurotransmitter responsible for muscle movement. It is released from motor neurons at the neuromuscular junction to stimulate muscle contraction.
Breaking down acetylcholine can lead to muscle relaxation because acetylcholine is a neurotransmitter that stimulates muscle contraction. When acetylcholine is broken down, the signal for muscle contraction is reduced, resulting in muscle relaxation.
Acetylcholinesterase, also known as AChE, is an enzyme which is critical to the function of animals from ants to elephants. This enzyme's sole responsibility is to break down the neurotransmitter acetylcholine. Acetylcholine sends messages between nerves, signaling muscle contractions. If the neurotransmitter was not broken down after it had served its function, the muscle involved would not be able to relax, and this could create spasms, paralysis, and other problems.
"A muscle cell remains contracted until the release of acetylcholine stops and an enzyme produced at the axon terminal destroys any remaining acetylcholine."
The presence of an enzyme called acetylcholinesterasethat degrades acetylcholine is what prevents an accumulation of the neurotransmitter and sustained muscle contraction. Acetylcholinesterase is an enzyme that can be found within the neuromuscular junction. Thus, when a nerve impulse causes the release of acetylcholine at the neuromuscular junction, there is a critical time in which the neurotransmitter can bind to receptors on the muscle before it is degraded.
Acetylcholine receptor is present on the sarcolemma of the muscle cells. This receptor is responsible for transmitting the signal to initiate muscle contraction when acetylcholine binds to it at the neuromuscular junction.
If the enzyme that breaks down acetylcholine is destroyed, acetylcholine levels in the body will increase. This can lead to overstimulation of muscles and nerves, causing symptoms like muscle twitching, paralysis, respiratory failure, and even death.
Acetylcholinesterase is always present in the synaptic cleft of a neuromuscular junction. It is responsible for breaking down the neurotransmitter acetylcholine, allowing for the termination of the signal transmission between the neuron and the muscle cell.
Acetylcholinesterase is an enzyme that breaks down acetylcholine into choline and acetate at the neuromuscular junction. This prevents acetylcholine from accumulating and allows for efficient signaling between the nerve cell and the muscle cell.
acetylcholine (ACh)
Acetylcholine is the excitatory neurotransmitter released by neurons innervating skeletal muscles. Acetylcholine release stimulates muscle contraction by acting at the nicotinic-acetylcholine receptor on the surface of the muscle cell.
Acetylcholine is the primary chemical transmitter released at the neuromuscular junction. It binds to acetylcholine receptors on the muscle cell membrane, leading to muscle contraction.
Nicotinic receptors are commonly present in the neuromuscular junction (neuromuscular endplate). They respond to acetylcholine released from the terminals of motor neurons by opening to allow deploarizing K+ flow.