ER>Golgi>Outside of the cell.
cytoplasm to ER to outside the cell
enzyme responsible in the insulin signaling pathway. phosphorylates substrates like IR.
Endoplasmic Reticulum --> Golgi Apparatus --> outside the cell
Examples of secretory proteins are collagen, insulin, and digestive enzymes of the stomach and intestine.
Insulin promotes various metabolic processes, including glucose uptake by cells, glycogen synthesis in the liver and muscle, and fat storage. However, it does not promote gluconeogenesis, which is the process of producing glucose from non-carbohydrate sources, as insulin actually inhibits this pathway. Therefore, insulin does not support the increase of blood glucose levels through gluconeogenesis.
Insulin synthesis begins in the pancreas's beta cells, where preproinsulin is synthesized in the rough endoplasmic reticulum (RER). It is then processed into proinsulin, which is transported to the Golgi apparatus, where it matures into insulin through the removal of the C-peptide. The mature insulin is stored in secretory granules until glucose levels rise, triggering exocytosis, which releases insulin into the bloodstream. This process helps regulate blood sugar levels effectively.
Type II diabetes is commonly associated with obese or overweight people because the fat within their bodies can hijack the insulin signalling pathway making cells insensitive to insulin. Soccer as a form of exercise can reduce the amount of fat (adipose tissue).
Afferent pathway
It is a long acting insulin.
Afferent pathway
Pathways of action are the activities, institutions, and decision points that Answer: shape law and public policy
Watch your footing on this pathway! I merely seek the pathway to success.