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What is the underlying cause of all porphyrias?

Updated: 8/19/2019
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The underlying cause of all porphyrias is a defective enzyme important to the heme biosynthesis pathway. Porphyrias are inheritable conditions.

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Q: What is the underlying cause of all porphyrias?
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What were porphyrias affecting heme biosynthesis in the liver called?

Hepatic porphyrias.


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What is the general presentation of acute porphyrias?

All of the hepatic porphyrias--except porphyria cutanea tarda--follow a pattern of acute attacks separated by periods during which no symptoms are present.


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What is the general presentation of non-acute porphyrias?

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What does underlying cause mean?

the underlying cause is the main reason or motive for an action or event


What is the medical condition porphyrias?

The porphyrias are disorders in which the body produces too much porphyrin and insufficient heme (an iron-containing nonprotein portion of the hemoglobin molecule).


What were porphyrias affecting heme biosynthesis in immature red blood cells called?

Erythropoietic porphyrias (erythropoiesis is the process through which red blood cells are produced).


Can people die from heart murmer?

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What is the cause of porphyrias?

Because heme is low, the synthesis path continues to produce precursor molecules. Each porphyria corresponds with an enzyme defect and an amassing of associated precursor.


When the patient is being treated for a condition that has an underlying cause?

code first the underlying disease


Are porphyrias considered rare disorders?

Considered a rare disorder.