residual solvents are leftovers that form a solution, toxic or non-toxic
To convert an assay value from dried basis to as-is basis, you need to adjust for the moisture content. The formula for this conversion is: As-is assay value = Dried assay value / (1 - Moisture content). For example, if the dried basis assay value is 90% and the moisture content is 5%, the as-is basis assay value would be 90% / (1 - 0.05) = 94.74%.
Potency is the purity of the compound ;this states % available of the main component without water and residual solvents Assay is defined as Potency plus water and residual solvents and other remaining fractions please note assay can also be expressed as as is basis or dry basis Assay and Potency are same if assay is exprtessed as as is basis please note Potency word is mainly used for Antibiotics and bilogicals courtsey ; CDER , USFDA ; Dr.Uttam Krishna
Non-ionic solvents, as organic solvents.
As xylene is a solvent, I would have to say a constant exposure could cause cancer! Most solvents are reported to be cancerous during long-term usage.
solvents are sniffed only
assay on as is basis includes the weight of water, residual solvents, moisture absorbed, if any. but assay on dried basis will remove all athe above by drying the sample under analysis.
what are five examples of solvents
Solvents are used to dissolve solutes.
THEY ARE solvents that can mix to form a new substance
a solution can have 3 solvents.
The principle of Rotatory cone vacuum dryer is, to absorb the moisture content & residual solvents present in the drug substance by vacuum & steam applying through external source. as a result the product can be dried regarding to the specifications.